|
KMID : 0385219970070030084
|
|
Korean Journal of Gerontology
1997 Volume.7 No. 3 p.84 ~ p.91
|
|
|
Feeding effects of super-100 yoghurt on body weight and biological activity of Sprague-Dawley rats
|
|
Choi Jin-Ho
Kim Dong-Woo
Kim Chang-Mok
Kim Hyun-Sook
|
|
|
Abstract
|
|
|
|
Sprague-Dawley male rats were fed experimental diet and also were orally administered with Super-100 yoghurt(Hankook Milk Co.) diluted in half with water for 4 weeks. Effect of Super-100 yoghurt on body weight gain, feed and gross efficiencies, triglyceride(TG) and total and LDL-cholesterol levels, atherogenic index(AI), hydroxyl radical and lipid peroxide(LPO) levels and superoxide dismutase(SOD) as a scavenger enzymes on oxygen radicals were evaluated. Administration of Super-100 yoghurt resulted in a marked inhibition(about 45%) in increase of body weight compared with control group for 4 weeks. Total food intake significantly decrease in 30% from 424.7±43.2 g to 301.0±33.4 g by administration of Super-100 yoghurt(p<0.001). Administration of Super-100 yoghurt resulted in a marked decrease in feed efficiency(30%) and gross efficiency(25%) from 18.20±2.92 and 4.10±0.67 to 12.83±1.13 and 3.11±0.49, respectively compared with control group(p<0.01). Triglyceride(TG), total cholesterol and LDL-cholesterol levels and atherogenic index(AI) in serum of rats significantly decreased in all 15% by administration of Super-100 yoghurt(p<0.05). Formation of hydroxyl radical in serum of rats significantly decreased in 63.1% from 5.39±1.44n mole/㎎ protein to 1.99±0.05 n mole/㎎ protein and lipid peroxide(LPO) level in serum of rats also significantly decreased in 46.3% from 47.55±3.60 n mole/㎖ serum to 25.52±3.72n mole/㎖ serum by administration of Super-100 yoghurt(p<0.001). Administration of Super-100 yoghurt resulted in a significant increase(about 15%) in superoxide dismutase(SOD) activity compared with control group for 4 weeks. These results suggest that administration of yoghurt such as Super-100 effectively can not only inhibit obesity and chronic degenerative diseases, but also can intervent the aging process.
|
|
|
KEYWORD
|
|
|
Super-100 yoghurt, Obesity, Triglyceride(TG), LDL-cholesterol, Hydroxyl radical, Free radicals, Atherogenic index, Scavenger enzyme, Superoxide dismutase(SOD)
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|